WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD FOR ESTIMATION OF NIMODIPINE CONTENT BY UVSPECTROSCOPIC METHOD

Rajesh S. Jadhav, Milind Ubale and Jagdish V. Bharad*

ABSTRACT

A Simple, specific, rapid, precise and accurate UV Spectrophotometric method have been developed and Validated for determination of Nimodipine formulation drug. Nimodipine showed the absorption maxima in at 239.0 nm and was linear for a range of 5 μg/ml–25 μg/ml with correlation coefficient of 0.9996. The validation of the above proposed method was done by carrying out precision and accuracy studies. The analytical method showed good Intra precision (Repeatability) with relative standard deviation 0.522% and Inter precision with relative standard deviation is 0.355% which is less than 2. The percentage recovery at three different levels i.e. 50%, 100% and 150% was found to be 49.9%, 99.1% and 149.6% respectively. The proposed method was validated for the parameter Specificity, Precision, Linearity and range, Ruggedness, Accuracy and recovery. Hence proposed analytical method for estimation of Nimodipine formulation drug by UV spectrophotometer in pharmaceutical can be applied for the routine quality control analysis.

Keywords: Validation, Nimodipine, UV Spectrophotometer.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More