WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

DEVELOPMENT OF NEW VALIDATED ANALYTICAL METHODS FOR THE ESTIMATION OF BOSENTAN IN BULK AND PHARMACEUTICAL DOSAGE FORM BY UV SPECTROPHOTOMETRY

Mastanamma Shaik, Pasupuleti Saidulu, I.S.Tejaswini. U . Annapurna

ABSTRACT

The present study describes a simple, accurate, precise, specific and highly sensitive methods for the determination of Bosentan present in pharmaceutical dosage forms. Bosentan exhibits maximum absorbance (λ max) at 269 nm (Method A) and Method B is an area under curve(AUC)method 264-274nm.The drug obeys the Beer- Lambert’s law in the concentration range of 2.5-15 μg/ml in two methods. The methods were validated and can be successfully applied to estimate Bosentan in pharmaceutical dosage forms. The proposed methods were validated in terms of linearity, precision and accuracy the present work provides an accurate and sensitive method for the analysis of Bosentan in bulk and tablet formulation.

Keywords: Bosentan , UV-Vis Spectrophotometry, AUC, tablets.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More