Abstract

AN INTERVENTIONAL, PROSPECTIVE PILOT CLINICAL TRIAL TO EVALUATE SAFETY AND EFFICACY OF PIHF IN IMPROVING IMMUNITY IN HEALTHY ADULTS

Dr. Veena Deo, Neha N. Dandewar, Pushpendra Kumar, *Dr. Gayatri Ganu and Dr. Ninad Naik

.

Abstract

Objective: The COVID-19 pandemic has imposed an excessive damage to the world as it is spreading with high rate and simultaneously with a high mortality. Within this pandemic situation, it is of high importance to strengthen immune system. Material and methods: 30 subjects were enrolled in the study and were treated with the test product for 30 days. Immunity parameters, subjective scales were assessed on baseline and day 30. Results: PFHI formulation was effective in increasing the GHQ-28 score by 152.5 % after 30 days. The energy audit frequency score distribution depicted that the “very high energy” and “high energy scores” were increased and the “very low energy” and “low energy” scores were decreased as compared to the baseline. The serum immunoglobulin levels in treated subjects were found to be increased by 39.93 % from the baseline. The digestive complaints were reduced. Occasional abdominal pain was reduced by 44.6%, heartburns were reduced by 34.2 %, and regurgitation and flatulence were decreased by 28.1 % and 25.8 % respectively. Other complications like bloating were reduced by 19.0 %, constipation was decreased by 14.1 % and post prandial fullness was reduced 17.1 %, in span of 30 days. All the parameters in the complete Hemogram were within normal range. There were no episodes of illness, infections, etc. Conclusion: This explains PFHI is an effective and safe formulation. PFHI is effective in enhancing the general health. It has potential action in increasing energy and reducing digestive complications.

Keywords: COVID-19, Immunity, Ayurvedic formulation, Digestive complications.