Abstract

INVESTIGATION ON BIOCHEMICAL AND ANTIMICROBIAL POTENTIAL OF EUPATORIUM ADENOPHORUM, A MEDICINAL PLANT SPECIES FROM WOKHA NAGALAND, INDIA

Benchilo Ezung*, Ranjan Dutta Kalita and Agastian Paul

.

Abstract

Throughout the course of history, plants and their derived extracts have been utilized for therapeutic purposes, spanning across numerous millennia. Even in contemporary times, medications derived from plants remain integral components of global healthcare systems. Eupatorium adenophorum is a significant botanical species with medicinal properties, which is recognized as being susceptible to environmental pressures in several regions across the globe. The current investigation focused on examining the antibacterial activity, antioxidant assay, total phenols, alkaloids content, and haemolysis activity of the plant species. The antibacterial activity of the ethanol extract of Eupatorium adenophorum was shown against Pseudomonas aeruginosa and Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of 2.5 mg/ml. The extract exhibited a significant level of antioxidant activity, measuring approximately 68.39%. The analysis revealed the presence of a significant concentration of alkaloids in the extract. The phenolic content of the extract was found to be significantly low, and no haemolytic activity was observed, suggesting that the extracts possess non-cytotoxic properties. Therefore, based on the findings of this study, it is recommended that more research be conducted to explore the antibacterial and antioxidant capabilities of Eupatorium adenophorum.

Keywords: Eupatorium adenophorum, medicinal plants, antioxidant, antimicrobial, MIC.