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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

METHOD DEVELOPMENT AND VALIDATION OF TAMSULOSIN HCL IN BULK AND TABLET DOSAGE FORM BY UV SPECTROSCOPY METHOD

M. Sivaganesh*, Dr. S. K. Senthil Kumar, S. Shabeena, A. Sivasankar, S. Siyan, D. Sneha, P. Sneha

Abstract

A Simple, rapid, accurate and economical UV Spectrophotometric method is developed for determination of tamsulosin hydrochloride in bulk and pharmaceutical dosage forms. In Acetonitrile, the λ max of the drug was found to be 224 nm. Using UV instrument (analytical), in this proposed method tamsulosin hydrochloride follows linearity in the concentration range 0.5 – 1.50μg/ml with a correlation coefficient of 0.999. Assay results were in good agreement with label claim. The relative standard deviation was found to be 0.398272 with excellent precision.

Keywords: Tamsulosin hydrochloride, U.V. Spectrometry, Acetonitrile.

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