Abstract

ADVANCES IN EMULGEL AS A TOPICAL DRUG DELIVERY SYSTEM

Siva S.*, V. Jeevith Kumar, Manikandan A., Sethupathi S., Kathick T. M., Dr. Sathish A.

Abstract

Emulgels, a type of biphasic semisolid formulation, have surfaced as a promising method for topical drug delivery. They combine the advantages of both emulsions and gels, resulting in a formulation that is both non-greasy and easy to apply, capable of delivering hydrophilic and lipophilic compounds alike. Studies have demonstrated that emulgels can address the challenges associated with conventional gels and emulsions, such as their inability to effectively transport hydrophobic medications and diminished stability during storage. The essential principles governing emulgel systems are based on physicochemical principles, and their features, including thixotropy, non-greasy properties, and emollient qualities, render them an excellent option for dermatological uses. Emulgels have effectively been utilized to transport various medications, such as amlodipine besylate, amphotericin B, and diclofenac sodium. Due to their capacity for controlled release, increased stability, and better patient adherence, emulgels have the potential to transform topical drug delivery. More research is necessary to thoroughly investigate their capabilities and tackle existing formulation and characterization challenges.

Keywords: Emulgels, topical drug delivery, controlled release, stability, patient compliance.