Abstract

CLINICAL EVALUATION OF GOKSHUR KSHEERAPAKA AND SHATAVARI KSHEERAPAK IN THE MANAGEMENT OF PITTAJAMUTRAKRICHCHRA: A RANDOMIZED CONTROLLED STUDY

Dr. Tehreen Mohammed Tarique*, Dr. Parag Narayan Deshmukh

Abstract

Urinary tract infections (UTIs) represent a significant global health burden, ranking as the second most prevalent infection after respiratory tract disorders, with an estimated 40– 50% of the female population experiencing at least one episode during their lifetime. While contemporary medicine offers a diverse range of pharmacological interventions, their utility is increasingly constrained by the emergence of multi-drug resistant (MDR) strains, significant side effects, high recurrence rates, and the economic burden of long- term therapy. In response to these challenges, the Ayurvedic corpus offers a rich repository of botanical interventions for the management of Mutrakrichchra (dysuria), a clinical entity that closely correlates with UTIs. The present study was designed to evaluate the safety and clinical efficacy of two specific Ayurvedic formulations— Gokshur Ksheerapaka[1] and ShatavariKsheerapaka—aiming to identify a therapeutic agent that offers high patient acceptability without the complications associated with conventional antibiotics. A randomized controlled clinical trial was conducted involving a total of 68 patients diagnosed with Mutrakrichchra secondary to urinary tract infection. Participantswere stratified into two cohorts: Group I (Trial Group, n=34) and Group II (Control Group, n=34). The trial intervention consisted of 40 ml of GokshurKsheerapaka administered twice daily, while the control cohort received ShatavariKsheerapaka in an identical dosage for a cumulative duration of 14 days, with an intermediate assessment on the 7th day. Therapeutic outcomes were evaluated through a comprehensive analysis of subjective clinical parameters recorded at baseline and post-treatment. The resulting data were subjected to rigorous statistical analysis to determine the relative efficacy of the two interventions in the management of urinary distress.

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