Abstract

ANALYZING BARRIERS OF SPONTANEOUS ADVERSE DRUG REACTION TO REPORTING AMONG HEALTHCARE PROFESSIONALS

*Aarush Awasthi, Aryan Srivastava, Akhilendra Singh, Vaibhav Mishra, Aadit Yadav, Ashish Tripathi

Abstract

Adverse drug responses (ADRs), often known as medicationrelated adverse events, are negative outcomes brought on by drugs. The World Health Organization (WHO) defines adverse drug reactions (ADRs) as "a response to a medication that is noxious and unintended used in man to treat." ADRs may be caused by an unanticipated mistake such an allergic response or an avoidable pharmaceutical error that results in a side effect from the delivery of medicine. ADRs can significantly hinder patients' quality of life and put more strain on the healthcare system. ADRs are one of the leading causes of morbidity and death worldwide, and they will remain a major public health concern due to the growing complexity of medications used to treat a variety of illnesses in an aging population. Adverse drug events sometimes have complicated, multiple causes. Adverse responses fall into three categories: allergic, idiosyncratic, and dose/drug related. Drug-related and dose-related adverse drug responses are mostly foreseeable, though occasionally inevitable, and are linked to the medication's dosage. The patient's susceptibility to the medicine and the combinations of medications utilized have a significant impact. Although it is somewhat prevalent, it usually does not result in serious ADR. An allergic drug response occurs when a patient experiences an inappropriate reaction to a medicine, which is typically preventable with a skin test beforehand or by efficient consultation and communication between patients and primary care institutions. The intensity of an idiosyncratic adverse medication reaction is frequently highly unexpected and is not well understood. The knowledge and attitudes of health professionals are the primary variables linked to underreporting of adverse drug reactions (ADRs), according to a large percentage of research that our group conducted in a systematic review. Here is the study that is conducted by our group that includes all the factors leading to adverse drug reactions to reporting among healthcare professionals.

Keywords: PV(Pharmacovigilance), Underrepoting, Adverse Drug Reaction (ADR), Patient Safety, adverse events, Primary care, general practice, home healthcare.