Abstract

SERUM LIPOPROTEIN COMPONENTS IN ISCHEMIC CEREBROVASCULAR STROKE PATIENTS.

*Dr. V. Bhagyalakshmi, Dr. V. Bhavani, Dr. G. Premkumar, Dr. M. Jaiprakash
Babu, Dr. G. Rajeswari

Abstract

Back Ground: 1. To study the risk factors in patients of ischemic stroke. 2. To correlate the risk factors with reference to lipoprotein abnormalities. 3. To study the role of lipoprotein components in ischemic stroke patients. Method: A total number of 60 patients admitted in the medical wards under the department of general medicine of government general hospital, Rangaraya medical college, Kakinada, were included. 40 age & Sex matched healthy individuals were also included in the study as controls for comparison. Results: Serum triglycerides, total cholesterol, LDL Cholesterol showed positive association with ischemic stroke compared to controls. Serum HDL Cholesterol showed inverse association with ischemic stroke compared to controls. Conclusion: LDL cholesterol (oxidized) initiate inflammatory response which has been linked to atherogenesis. HDL cholesterol prevents oxidation of LDL cholesterol and is protective against ischemic stroke.

Keywords: Ischemic stroke, Triglycerides, Total cholesterol, HDL, LDL, VLDL cholesterol.