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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

CHARACTERISATION OF CARBAPENEM RESISTANT GRAM NEGATIVE MICROBES IN A BURN UNIT OF TERTIARY HEALTH CARE CENTRE

Antariksha Deep, Priyanka yadav, Ravi Kumar, *Seema Mittal, Kiran Bala, Uma
Chaudhary

Abstract

Back ground: Burn wounds are major challenge for clinicians in a burn unit, because these are responsible for more than 50% nosocomial infection and fatality in burn patients. Recently a change in prevalent microbial flora has been noticed in burn patients and therefore this study has been done to know the prevalent micro organism and multi drug resistance in burn ward. Aims and objective: To know the changing bacterial profile and multi drug resistance in burn patiens. Material and Methods: This study was conducted on 1074 pus swabs from burn patients received in laboratory during a period of one year from Jan to Dec 2013. The micro organisms were identified as per standard protocol and their antibiotic susceptibility was performed as per CLSI guidelines. Study design: This was a retrospective study done in department of Microbiology of Pt. B.D.Sharma PGIMS, Rohtak. Results: Infection rate of 88.4% was found in burn unit with an increase in isolation rate of Klebsiella spp.and Acinetobacter spp. However Pseudomonas spp. was most common followed by Staphylococcus aureus. In parallel an increase prevalence of multi drug resistant strains was noticed. Conclusion: As these nosocomial strains can be source for infection outbreaks in other units as well, therefore strict hand hygiene practices is required among hospital staff members to inhibit the cross transmission of microbes.

Keywords: Burns, carbapenem, multi drug resistance, Pseudomonas spp.


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