Abstract

ANTIMICROBIAL ACTIVITY OF PHYLLANTHUS NIRURI AGAINST DIFFERENT HUMAN PATHOGENIC BACTERIAL STRAINS

Rajesh Pratap Singh*, Anju Pal and Krishan Pal

Abstract

Use of herbal medicine over synthetic drugs has become increasingly popular due to the various side effects and pathogen resistance after long term uses of synthetic drugs. In order to overcome with these issues alternative drugs from natural resources need to develop. Phyllanthus niruri (Linn) member of family Euphorbiaceae is one of the potential medicinal plant, however very less known about its medicinal usage and active ingredients. In this study antimicrobial activity of ethanolic and methanolic extract of Phyllanthus niruri was tested against six major human pathogenic microbial strains viz; Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Streptococcus mutans and Salmonella typhae. The results indicate that both the organic extracts (Ethanol and Methanol) of Phyllanthus niruri showing broad spectrum of antimicrobial activity.

Keywords: Antimicrobial activity, Ethanolic and Methanolic extract, Major human pathogenic microbial strains, Phyllanthus niruri.