Abstract

ABNORMAL LIVER FUNCTION TEST ASSOCIATED AMONGST DIABETES PATIENTS IN THE DHAKA CITY OF BANGLADESH.

Lutful Haque Saran, Mohsina Mukti, Md. Reyad-Ul-Ferdous*, A. H. M. Mahmudur Rahman, Md. Mamun- Ur- Rashid, Naim Islam, Adnan Taher

Abstract

Objective: In recent era diabetics becomes most pathological condition worldwide. Maximum populations in both develop and developing countries suffering from diabetic. There are several diseases associated with diabetics like as kidney, liver, heart diseases etc. Methods: In this study, retrospectively study conducted at BUSB. Then data were entered into computer and results were calculated with the help of Microsoft Excel. Results: In the study, it has been found that the percentage of female is found to be 53% with diabetes and the percentage of male is found to be 46%.The level of Serum glutamic pyruvic transaminase (SGPT) also called (Alanin Transaminase) is found to be relatively high amongst the diabetes patient who reflects that the liver problems are prominent amongst diabetes patients. The average value of alanine transaminase which is released from liver is found to be 47.41+2.37 IU/L. Mean level of creatnine is found to be 0.93+0.022 mL/min (Normal range: 0.4to1.2 mL/min). HbA1c is amount of glycated hemoglobin is a form of hemoglobin that is measured primarily to identify the average plasma glucose concentration over prolonged periods of time. The average HbA1c is found to be 10.81865 + 2.126 mmol/mol. Lipid profiles are other important parameter which is play vital role amongst the health of diabetes patients. The mean value of cholesterol, TG, LDL, HDL is found to be 193.032353 + 5.962(mg/dl), 176.13+ 10.43 (mg/dl), 127.6262+ 4.8 (mg/dl) and 41.02381 + 1.072 (mg/dl). The most important observation of the study is that the age group of 51.48 years had the highest incidence of diabetes with liver problems. The highest number of patients consumes oral medications which is 53.043%.The average SGPT value amongst the patient is also high which 47.41UI/L. This reflects that the liver problems are prevalent in the diabetic population. Conclusion: Further investigation requires identifying other diseases related with abnormal liver function test or diabetic’s diseases.

Keywords: Diabetics, Abnormal Liver function, cholesterol, Triglyceride (TG), Low density lipoproteins in blood (LDL), High density lipoproteins in blood (HDL), Serum glutamic pyruvic transaminase (SGPT), Bangladesh.