Abstract

A REVIEW ON BIOMARKER AND ITS POTENTIAL APPLICATIONS

Swarupananda Mukherjee*, Subhasis Maity, Abhishek Ghosh, Partho Pratim Biswas, Piyali Khamkat

Abstract

Biomarkers provide a dynamic and powerful approach to understand the spectrum of various diseases including neurological diseases with application in observational and analytic epidemiology, randomized clinical trials, screening, and diagnosis. Successful implementation of biomarkers in drug development can decrease development timelines by allowing earlier go/no go decisions and increase the success of drugs in clinical trials by rationally guiding dose and indication selection. Biomarkers has gathered immense scientific as well as clinical value and is most favored and incorporated in practice of medicine. Its ability to reflect the entire spectrum of disease from the earliest manifestations to the terminal stages guides in proper treatment of the individual reduces the chances of casualties and even economic losses. This substances and their ability for the discovery of new drugs opens the door for treatment of diseases like Alzheimer‟s and various type of rare and deadly cancer. The abilities and potential of biomarkers allows a company for selection and production of specific drug products and also aids them for mapping out future directions. Thus overall biomarkers are a powerful tool which helps in the identification of various health effects, discovery and evaluation of various drug products and vaccines.

Keywords: Biomarkers, Drug products, Mapping, epidemiology.