Abstract

PHARMACOGNOSTICAL AND PHYTOCHEMICAL ANALYSIS OF TRIPHALADI GHANA-VATI - AN AYURVEDIC POLYHERBAL FORMULATION FOR SENILE IMMATURE CATARACT

Hitesh Bhati*, Harisha C. R., Shukla V. J. and Manjusha R.

Abstract

On comparing signs and symptoms of senile cataract according to Ayurvedic texts this condition can be categorised under Jara Janya Vyadhi (Senile disorders). Rasayana drugs mentioned in Ayurvedic classics are said to be possess Rejuvenating and Chakshushya properties i. e. Beneficial for eyes. Triphaladi Ghana-Vati contains Eleven drugs which are known for their potent psycho-physical rejuvenating action/Rasayana properties, Adaptogenic properties, Anti-AGE properties (Anti- Advanced glycation end products), and Immunomodulatory actions. In the present study drug has shown encouraging clinical outcome in senile immature cataract. The polyherbal compound Triphaladi Ghana vati was subjected to Pharmacognostical evaluation, Physicochemical properties, phytochemical analysis and HPTLC studies. Sclerides, Silica deposits, Chollenchyma cells, Pitted vessels, Starch grains, Trichomes, Crystal fibres, Stone cells, Oleorasins, Acicular crystals, Annular vessels, Oil globules, Epicarp, Rod shaped crystals were found on Pharmacognostical evaluation. Alkaloids Tannin & Phenolic compounds, Flavonoid, Glycosides, Anthroquinon glycosides, Carbohydrate, Sugar and Steroids were present on carrying Phytocostituents evaluation. Physicochemical constants like pH, Loss on drying, Water soluble Extract, Alcohol soluble extract and Total Ash value were evaluated along with organoleptic characteristics.

Keywords: Triphaladi Ghana Vati, Cataract.