Abstract

ORAL TOXICITY STUDY OF VERNONIA CINEREA AQUEOUS LEAF EXTRACT IN SWISS ALBINO MICE

*Dr. S. N. Suresh, Varsha V. and Prejeena V Cartier Replica Breitling Replica

Abstract

The study aimed to check for the toxicity effect of Vernonia cinerea leaf aqueous extract in Swiss Albino mice at different dosage levels. The extract was administered orally at dose levels of 5 mg/kg, 50 mg/kg, 300 mg/kg, 1000 mg/kg and 2000 mg/kg. Clinical and behavioural signs were observed for 14 days. The animals were checked for mortality during the study period. Home cage activities and hand-held observations were noted to analyse changes in the mice during the administration period of the plant extract. The results revealed that Vernonia cinerea aqueous leaf extract was safe up to 2000 mg/kg dose levels in mice. No changes in behavioural and clinical signs were observed. No mortality was seen after administration of Vernonia cinerea leaf extract Omega Replica Repliche Orologi.

Keywords: Toxicity, Vernonia cinerea, Aqueous, Swiss Albino mice, Mortality.