Abstract

A STUDY ON IN VITRO ANTI-UROLITHIATIC ACTIVITY OF AQUEOUS EXTRACTS OF GREEN TEA & LEMON

Kartheek Chegu*, K. Mounika, M. Rajeswari, N. Vanibala, P. Sujatha, P. Sridurga and D. R. Brahma Reddy

Abstract

A kidney stone, also known as a renal calculus is a solid concretion or crystal aggregation formed in the kidneys from dietary minerals in the urine. Urolithiasis is a complex process that occurs from series of several physicochemical event including super-saturation, nucleation, growth, aggregation and retention within the kidneys. Data from invitro, in- vivo and clinical trials reveal that phytotherapeutic agents could be useful as either alternative or an adjunct therapy in the management of Urolithiasis. Medicinal plants / natural products are more useful for body because they promote the repair mechanism in natural way. Plant species of Green tea and Lemon, have been reported to posses antiurolithiatic property. In this study aqueous, extracts of Green tea plus Lemon and standard for dissolving kidney stones- calcium oxalate by an invitro model. To check their potential to dissolve kidney stones- calcium oxalate by an in-vitro model for Green tea and Lemon and cystone as a standard compound collected from market. In the present study we found that Green Tea aqueous extract and Lemon juice are decreases formation of kidney stones due to presence of high rich contents of phenolic and flavanoids.

Keywords: Kidney Stones, Urolithiatic, Calcium Oxalate, Green Tea and Lemon.