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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

NEW AND EFFICIENT GREEN CATALYST ONE-POT SYNTHESIS OF BENZIMIDAZOLE AND DERIVATIVES

Gurumeet C. Wadhawa*, Vitthal S. Shivankar, Yashwant A. Gaikwad, Nilam S. Dhumale, Charansingh H. Gill and Laxman V. Gavali

Abstract

A series of substituted benzimidazole were prepared through the onepot reaction of o-phenylenediamine with various aromatic aldehydes in the presence of ferrous sulphate as catalyst both in Ethanol and water as solvent under Sonication and Grinding. The reactions proceed smoothly in excellent yield, high chemo selectivity and with an easy work-up with better yield.

Keywords: Benzimidazole, Ferrous sulphate Aldehyde, Green Route.

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