Abstract

ETHANOBOTANICAL CHARACTERIZATION OF COCCINIA INDICA AGAINST URINARY TRACT INFECTION

Deepa M. and Sharly Elgal N*.

Abstract

Medicinal plants are the backbone of traditional medicine in the last few decades. Several screening studies have been carried out in different parts of the world. This has been brought about by the acknowledgement of the value of medicinal plant as potential source of new compounds of therapeutic value and as a source of new compounds in drug. Most of the several traditional medicines in existence are derived from several medicinal plants which prevent detrimental effects to a human being. Coccinia indica has been widely utilised as a home remedy for several ailments. The leaf of coccinia indica has various pharmacological activities such as antibiotics, antidiabetics, anticancer, antimalarial. Coccinia indica serves to be a dynamic medicine in the treatment of urinary tract infection. Most common bacteria that infects urinary tract are E. coli, Klebsiella pneumonia, Pseudomonas, Proteus Vulgaris. Antibiotic drugs have a greater capacity to destroy bacteria or suppress their growth. MIC was performed to determine the concentration of the extract that is lethal to the target bacteria by broth dilution method Phytochemicals are secondary metabolites that extensively used in therapeutic purpose. Phytochemical such as tannin, saponin, protein, alkaloids, flavonoids and etc are extracted, screened & identified in the plant using three different solvents like DMSO, Ethanol, and Propanol. Among the three solvents, the ethanol extract has a greater activity in the estimation of medicinal compounds which tends to prepare the desired medicine.

Keywords: Phytochemical screening, coccinia indica, urinary tract infection, MIC, secondary metabolites, Antimicrobial activity.