WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60


Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here


Track Your Article



L. Matsyagiri*, P. Jagadeesh, B. Mounika, V. Srinivas, V. Theja, Madhiha Jabeen and Dr. K. Hemamalini


Tinidazole is a synthetic antiprotozoal agent. It demonstrates activity both in vitro and in clinical infections against the following protozoa: Trichomonas vaginalis, Giardia duodenalis (also termed G. lamblia), and Entamoeba histolytica. A simple, sensitive, accurate and reproducible UV/visible spectrophotometric method were developed for the determination of Tinidazole in bulk and pharmaceutical dosage forms. Drug obeyed beer‟s law in the concentration range of 2-20 μg/ml. The method was validated for several parameters such as Linearity, Accuracy, Precision and Robustness as per the ICH guidelines. The drug exhibited maximum wavelength (nm) in 0.1N Sodium hydroxide solutions, 375 nm when compared with 0.1N Hydrochloric acid, Ethanol, and Distilled water due to the effect of solvent and chromophoric group. It was conclude that the drug, Tinidazole showed absorption maximum (λmax) in different manner in different solvents like 0.1N Hydrochloric acid, Ethanol, Distilled water and 0.1N Sodium hydroxide solution at 294 nm, 312 nm, 319 nm and 375 nm respectively. The percentage recovery values which is close to100 % indicates reproducibility of method and there is no interference from the excipients presents in the formulation (tablets) that developed method was found to be sensitive, accurate, and precise and the most reproducible result. The authors conclude that the proposed spectrophotometric method for the estimation of Tinidazole can be used for routine analysis of Tinidazole in bulk as well as in tablet dosage form.

Keywords: Tinidazole, UV Spectrophotometer, Validation, ICH guideline.

[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More