WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60


Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here


Track Your Article



Md. Abdullah Al Masum, Mohammad Shah Hafez Kabir*, Mohammed Shoibe, Mahmudul Hasan, Nishan Chakrabarty, Md. Jakiul Islam, Monisha Basak, Md. Nazmul Hasan, Md. Hosne Mobarak Chowdhury, Mohammed Abu Sayeed


Objectives: The present study was to investigate analgesic action of the methanol extract of Phyllanthus sikkimensis. Methods: The animals were submitted to acetic acid-induced writhing test and Formalin induced licking test to assess analgesic activities, respectively. Two doses 400 and 200 mg/kg were administered for testing. Results: The methanol extract of P. sikkimensis (MEPS) at both doses, exhibited a significant (p < 0.05 - < 0.01) dose-dependent analgesic activity in acetic acid writhing test and Formalin test. In acetic acid-induced writhing test, oral administration of MEPS (200 and 400 mg/kg) also decreased the writhing significantly while compared to control. The dose 400 mg/kg showed maximum percentage of pain inhibition 45.63% and 65.73% for respectively. Diclofenac sodium (10 mg/kg) was used as reference analgesic drugs. MEPS (200 and 400 mg/kg) significantly suppressed the licking activity in both phase of the formalin-induced pain in mice in a dose dependant manner. The reference analgesic drug Diclofenac sodium (10 mg/kg) also significantly inhibited the licking activity against both phases of formalin induced pain. Conclusions: The leaves extract has potential analgesic activity. The present study supports the use of P. sikkimensis in different pain states.

Keywords: P. sikkimensis, analgesic, Acetic acid writhing test, Formalin.

[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More