World Journal of Pharmaceutical Research (WJPR) has indexed with various reputed international bodies like :

WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.453

ICV : 90.8

WJPR Citation

	All	Since 2020
Citation	8502	4519
h-index	30	23
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Abstract

AN OVERVIEW: GASTRORETENTIVE DRUG DELIVERY SYSTEM

Hitesh P. Jagtap*, Prof. Trupti V. Kadam, Prof. (Dr.) Avinash B. Darekar

Abstract

Gastroretentive drug delivery systems (GRDDS) are an important area of oral controlled-release research, targeting prolonged gastric residence time (GRT) to enhance the bioavailability and therapeutic performance of drugs with narrow absorption windows, instability in alkaline pH, or requiring local gastric action. Human gastric physiology with gastric emptying increasing from 1–2 h in fasted to over 4 h in fed state, pH ranging 1.2–3.5, and migrating motor complex cycles of 90–120 min provides the basis for GRDDS development. Major approaches include floating systems (density

Keywords: Gastroretentive drug delivery system, floating system, controlled release.

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