Abstract

EXPLORING BIOHERBAL POLYMERIC DRESSINGS FOR ENHANCED DIABETIC WOUND HEALING: EMPHASIS ON CATHARANTHUS ROSEUS

Naveen Kumar M.*, Sugavanam C., Kajendiran K. M., Dr. M. Ranjith Kumar, Anushree V., Dr. S. Parthasarathi

Abstract

Diabetic wound healing continues to be a significant therapeutic hurdle because of extended inflammation, oxidative stress, insufficient tissue regeneration, and a heightened vulnerability to infection. Traditional wound dressings primarily act as protective barriers and frequently do not effectively aid the complex biological processes essential for proper healing under diabetic conditions. In recent years, bioherbal polymeric dressings have surfaced as a promising strategy by combining medicinal plant extracts with biocompatible polymer systems. This review investigates the potential of these dressings to improve diabetic wound healing, focusing particularly on Catharanthus roseus. This plant is historically recognized for its antidiabetic, antioxidant, and wound-healing properties, making it an ideal candidate for treatment in diabetic wounds. The review also addresses the beneficial role of Curcuma longa, especially in managing inflammation and the microbial load typically associated with chronic diabetic wounds. Additionally, the importance of chitosan–alginate polymeric systems is emphasized by their biocompatibility, moisture-retaining properties, and ability to deliver herbal bioactives in a controlled manner. Instead of presenting experimental results, this article delivers a conceptual and evidence-based overview of how the integration of selected bioherbs with polymeric dressings could provide a multifunctional approach to diabetic wound management. By merging insights from disease understanding, plant-based treatments, and polymer science, this review presents a clear and practical viewpoint for future research and advancement in diabetic wound care.

Keywords: Diabetic wound healing; Bioherbal dressings; Catharanthus roseus; Curcuma longa; Chitosan–alginate; Polymeric wound dressings.