Abstract

COMPARATIVE CLINICAL EVALUATION OF VIRECHANA KARMA AND JALKUMBHI BHASMA IN HYPOTHYROIDISM

Panwar G.*, Sharma K., Srivastava A. K.

Abstract

With the increased shift toward economic growth and the rising influence of Western lifestyles over the past few decades, the prevalence of lifestyle disorders has escalated to concerning levels among the Indian population. Hypothyroidism is a common endocrine disorder marked by insufficient thyroid hormone production, leading to slowed metabolism. It mainly affects women and presents with fatigue, weight gain, cold intolerance, dry skin, constipation, and depression. All metabolic activities are governed by Agni (Jatharagni, Dhatwagni, Bhutagni). Though hypothyroidism is not directly described in Ayurveda, its features correlate with Dhatwagnimandhya, where hypofunction of Jatharagni leading to impaired Dhatwagni forms the basis of disease development. Conventional management of ypothyroidism relies mainly on synthetic hormone replacement such as levothyroxine, often overlooking the underlying causes and the long-term effects of lifelong therapy. Ayurvedic interventions aim to naturally improve thyroid function, reduce dependence on synthetic drugs, and promote overall well-being, thereby offering a safer, effective, and sustainable treatment approach. The study, entitled ―Comparative Clinical Evaluation of Virechana Karma and Jalkumbhi Bhasma in Hypothyroidism‖, was conducted in 40 patients. They were selected on the basis of standard inclusion and exclusion criteria and randomly allocated totwo different treatment groups: Group-A (Virechana Karma) and Group B (Jalkumbhi Bhasma). The total duration of treatment was 2 months, and follow-up was done 1 month after completion of treatment. Both interventions were effective, but in the overall improvement of the patients, “Group-A” had better results than “Group-B”. For better scientific validation, further research studies and clinical trials should be conducted with a larger sample size and a longer treatment duration.

Keywords: Hypothyroidism, Dhatwagnimandhya, Virechana Karma, Jalkumbhi Bhasma.