Abstract

FORMULATION AND EVALUATION OF HERBAL CREAM FOR SUPPORTING SKIN HEALTH AND CIRCADIAN BALANCE

*Shaijan Yakub Shaikh, Mayur Mangate, Suraj Shinde, Akshada Sawant, Abhishek Pawar

Abstract

In recent days, every person is facing a major problem with Insomnia, Stress, mental disturbance, dryness and sleep disturbances. So, Herbal-based topical formulations are increasingly preferred due to their safety profile and therapeutic effectiveness. Cedarwood oil possesses notable soothing and calming effects, Anti-inflammatory activity, Antioxidant activity, and Moisturising/supportive effect, whereas Chamomile oil is recognised for its stress reduction and nervous system relaxation, skin smoothing and healing activity, antioxidant activity, sedative and anxiolytic Activity. The present work focuses on the development and evaluation of a Herbal Cream prepared using essential oils of Cedarwood oil and Chamomile oil by using the fusion method. The cream Base was formulated using Olive oil, stearic acid, cetyl alcohol and Emulsifying wax. The main aim was to create a stable, skin-compatible herbal cream with possible dermatological activity. Method: In our present study, we formulated 4 different formulations, F1, F2, F3, F4, by including different concentrations of liquid oil phase and water-based and evaluated by using various parameters such as physical appearance, viscosity, pH, phase separation, Spreadability, Stability studies, Irritability, wash ability, and got desirable results with all the tests. Results: Among the four formulations (F1, F2, F3 and F4), the formulation F3 was having Pleasant Odour, Off-white in color, non-irritant to the skin and Stable. Also, the formulations F1, F3 and F4 showed no redness or edema or erythema and irritation during irritancy studies. Conclusion: The formulated herbal cream showed acceptable physical properties, stability, and good skin compatibility during evaluation. The combination of natural ingredients demonstrated supportive antioxidant, soothing, and skin-protective effects that may help maintain healthy skin and support skin circadian rhythm.

Keywords: Herbal Cream, Circadian Rhythm, Cedarwood Oil, Chamomile Oil, Peppermint Oil, Essential Oils, W/O Emulsion, Stability Study, Topical Formulation.