Abstract

FUTURE GENERATION MEDICATION FOR DIABETES USING NANOTECHNOLOGY

Manorama Kumari*

Abstract

Diabetes mellitus is defined as a group of metabolic disorders characterised by hyperglycaemia. Around 387 million people around the world suffer from it and it is estimated that diabetes mellitus directly is responsible for around 4 million deaths per year. Nanotechnology can play a significant role in monitoring, repairing, control, and even constructing human biological system at cellular level. Medicine specific nanotechnology is commonly referred to as Nano medicine may be the most important part of having diabetes in getting insulin administered in the body. Nano technology is being used in non invasive approaches to insulin deliver and to engineer more effective vaccine cell and gene therapies for type 1 diabetes. In one such famous study insulin is protected with a bio composite consisting calcium phosphate, polyethylene glycol and milk protein. This protects the capsule from harsh GIT environment. Along with the oral route, insulin can be inhaled through the nasal openings using nanotechnology that leads them direct into the blood stream through lungs without degradation. Number of nano particles including calcium phosphate, porous hydroxyapatite and polymer nano particles has been tested for inhalation type insulin delivery with great success. Recent advancement in nano technology researches will surely lead to new ways of fighting the disorder with more success.

Keywords: diabetes mellitus, nanotechnology, oral insulin, inhalable insulin, improved technologies.