Abstract

MICROENCAPSULATED KETOPROFEN LOADED SUPPOSITORIES FOR RECTAL ADMINISTRATION.

Sidhartha Parida*, Dr. Shradhanjalipatra

Abstract

Alternative route of drug delivery and drug administration as drawn the attention of pharmaceutical researchers for past few decades. The sole aim of such approach is to either have a reduced side effects of the active principles or to mask its taste or achieving of other desired properties for patient benefit, out of all approaches one is delivery through rectal region which offers advantages over other routes and also is preferred area of drug delivery when most convenient oral route fails in certain cases.[1,2] Suppositories dosage system plays a major role in rectal administration but usage of fatty bases sometimes withdraws patient acceptance thus water soluble bases are more preferred. But use of water soluble bases restricts sustain ability of drug release thus promoting modification in formulation aspect of dosage form development.

Keywords: .