Abstract

ANALYSIS OF THE MONOSODIUM GLUTAMATE ON NEUROTRANSMITTERS USING QUANTUM METHOD

Manuel Aparicio-Razo, Oscar Sánchez-Parada, David César Malpica-Moreda, Manuel González-Pérez*

Abstract

Monosodium glutamate (GMS) is a sodium salt used as enhancer additive flavor. This GMS is one of the chemicals responsible for maintaining the flavor of long-lasting food. According to studies carried out, consumption of this additive can cause various side effects. Among the most common side, effects of GMS are headaches, nausea, migraines and muscle spasms; in extreme cases may have epilepsy, and heart irregularities. The objective of the study is to determine, using the semi-empirical method of chemical quantum SE-ZINDO/1), which neurotransmitter has a higher affinity with the GMS. Hyperchem Professional software performed Molecular Modelling and analysis of the GMS and nine of the major neurotransmitters. (Hyperchem, Hypercube, Multi on for Windows, series 12-800- 1501800080. Multi On, southern 1236-301 Tlacoquemecatl insurgent Col. del Valle, Mexico, Benito Juárez, CP 03200). The result of the simulations of the quantum poles reveals that this additive can oxidize Adrenaline, as well as cross bands related to this neurotransmitter.

Keywords: Monosodium Glutamate, Neurotransmitters, Quantum Method, Hyperchem, SE-ZINDO/1.