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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

TAMARIND WATER-PROMOTED SYNTHESIS OF AMINO-SCHIFFâ€™S BASES AND 1-ARYLMETHYL-2-ARYLBENZIMIDAZOLES UNDER GRINDING METHOD: A GREEN ALTERNATIVE APPROACH

Rammohan Pal*

Abstract

An efficient and eco-friendly procedure was developed for the green synthesis of various amino-Schiff’s bases and 1-arylmethyl-2- arylbenzimidazoles in high yields by tamarind water-promoted condensation of o-phenylenediamine with aromatic aldehydes under grinding protocol. This method is experimentally simple, clean, high yielding, and with reduced reaction times. The product is purified by simple filtration followed by crystallisation with ethanol and drying processes.

Keywords: Green synthesis, amino-Schiffâ€™s bases, 1-arylmethyl-2- arylbenzimidazoles, grinding, tamarind water.

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