Abstract

PHYTOCHEMICAL ANALYSIS AND ANTIBACTERIAL PROPERTIES OF TINOSPORA CORDIFOLIA LEAVES EXTRACT AGAINST HUMAN BACTERIAL PATHOGENS

Mohammed Ali Hussein* and Bhutada S. A.

Abstract

Tinospora cardifolia is a large deciduous climbing shrub; the extract of the plant is used as a remedy for many diseases. In the present study the aqueous, methanol, ethanol and acetone extract of Tinospora cordifolia, leaves extract were screened for the presence of phytochemical components and tested for antibacterial activity against Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Enterobacter aerogenes, Pseudomonas aeruginosa, Salmonella typhimurium, Salmonella typhi, Staphylococcus epidermidis and Proteus vulgaris. Results revealed the presence of anthraquinones, alkaloids, saponins, tannins, glycosides and phenolics. The acetone extracts had wide range of antibacterial activity against bacterial pathogens than the ethanol and methanol extract, where as aqueous extract were slightly higher antibacterial activity as ethanol extract. Antibacterial activity of various extract of leaves of Tinospora cordifolia would lead to the establishment of some compounds that could be used to formulate new and more potent antimicrobial drugs of natural origin.

Keywords: Tinospora cordifolia, leaves extracts, Phytochemical Screening, antibacterial activity.