Abstract

DEVELOPMENT AND OPTIMIZATION OF UV-VIS SPECTROSCOPY - A REVIEW

Govinda Verma* and Dr. Manish Mishra

Abstract

UV-VIS Spectroscopy is the term used for the analytical evaluation of the different types of the solvents and substances. UV- Visible spectrometers have been in general use for the last 37 years. Spectroscopy is generally preferred especially by small-scale industries as the cost of the equipment is less and the maintenance problems are minimal. The method of analysis is based on measuring the absorption of a monochromatic light by colorless compounds in the near ultraviolet path of a spectrum (200-400nm). The pharmaceutical analysis comprises the procedure necessary to determine the “identity, strength, quality and purity” of such compounds. It also includes the analysis of raw material and intermediates during the manufacturing process of drugs. It is well known that the dissociation constant is a most important parameter in development and optimization of a new compound for effective formulation development.

Keywords: UV- VIS Spectroscopy, Optimization Techniques, Electrochemical methods.