Abstract

ANTIBACTERIAL ACTIVITY OF DIFFERENT SOLVENT EXTRACT OF OPERCULINA TURPETHUM (L.) SILVA (ROOT) AGAINST IMPORTANT SPECIES OF BACTERIA

Kiran B.*, Jyothi Bala Chauhan and Padmini N.

Abstract

Antibacterial activity of different solvent extracts viz., petroleum ether extract, benzene, chloroform, methanol and ethanol extracts of root of Operculina turpethum (L.) was tested against six bacterial species viz., Escherichia coli, Enterobacter aerogenes, Klebsiella oxytoca, Proteus vulgaris, Bacillus cereus and Staphylococcus aureus at 500, 1000, 1500 and 2000ppm concentration. Among the five solvent extract tested, significant activity was recorded in methanol extract (25 to 30mm inhibition) compared to synthetic antibiotic Gentamycein at 25mg concentration. Methanol extract was followed by ethanol and recorded (8mm to 11mm inhibition) moderate activity in all the test bacterial species tested.

Keywords: Operculina turpethum, Antibacterial activity, synthetic bacteria.