Abstract

ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF ETHANOLIC EXTRACT FROM OPHIOCOMA ERINACEUS AND OPHIOMASTRIX ANNULOSA

S. Senthikumari and K. Revathi*

Abstract

In high-throughput search for bioactive compounds under resourcelimited settings from brittle star, the ethanolic extracts of the test samples were screened for antioxidant and antibacterial activity. Antioxidants due to their scavenging activity are useful for the management of many diseases. DPPH stable free radical method is a sensitive way to determine the antioxidant activity of O.erinaceus and O.annulosa extracts, antibacterial assay was performed against human pathogens namely; Bacillus sps, Pseudomonas aeruginosa, Proteus sps and E.coli using turbidimetric method. The results suggest that O. erinaceus and O. annulosa exhibited broad spectrum of antibacterial activity.

Keywords: Antioxidant, DPPH, Antimicrobial, Ophiocoma erinaceus and Ophiomastrix annulosa.