Abstract

PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF VARIOUS EXTRACTS OF CLERODENDRU M PANICULATUM LINN.

*Jeenu Joseph, Lincy Joseph, Mathew George and Bindhu A. R.

Abstract

Clerodendrum paniculatum Linn. of Verbenaceae family is used for the treatment of various diseases like asthma, typhoid, cancer and jaundice. Phytochemical screening revealed the presence of alkaloids, terpenoids, sterols, flavanoids, phenolics, carbohydrates and glycosides. The investigation was undertaken to appraise the antioxidant protection of different extracts of Clerodendrum paniculatum Linn. using beta carotene bleaching assay and nitric oxide radical scavenging assay. It was found that ethyl acetate extract has good free radical scavenging activity than other extracts by both methods. In these testing a significant correlation existed between concentration of the extracts and percentage inhibition of free radicals. The results clearly indicate that Clerodendrum paniculatum Linn. Is effective against free radical mediated diseases.

Keywords: Verbenaceae, Clerodendrum paniculatum Linn., beta carotene bleaching assay, nitric oxide radical scavenging assay.