Abstract

IN VITRO ANTHELMINTIC ACTIVITY OF CRUDE EXTRACTS OF RIPE AND UNRIPE SEED AND PEEL EXTRACT OF MALUS DOMESTICA

Ashish Kumar*, Harsh Kumar Baranwal, Kajal Ruhela and Pankaj Nainwal

Abstract

The most common digestive system infections are helminth infections. It affect more than two billion people worldwide.[4] In region of rural poverty in the tropics where prevalence is greatest simultaneous infection with more than one type of helminthes is common. Parasitic diseases cause ruthless morbidity affecting principally population in endemic areas. The gastro-intestinal helminthes becomes resistant to currently available anthelmintic drugs therefore there is a foremost problem in treatment of helminthes diseases. The current study reveals the potential of herbal drug in crude form used in helminthes infection or against heminthes. The hydroalcohoilic extract of peel and seed of Malus domestica (Apple) was taken against Pheritima at dose level of 0.25,0.5.1.0 mg/ml concentration. The results are compared with the standard drug Piperazine (0.25 & 0.5 mg/ml) and albendazole (0.25mg/ml) concentration and it was found that the extract is having significant potential against helminthes infection.

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