Abstract

EVALUATION OF ARISTOLOCHIA BRACTEOLATA LINN. FOR ANTIMICROBIAL ACTIVITY

*A. Freeda Rose, S. R. Senthil Kumar and T. Francis Xavier

Abstract

The antibacterial activities of the various organic solvent extracts of Aristolochia bracteolata leaf were assayed in vitro by the Disc diffusion method against ten opportunistic bacterial pathogens such as Klebsiella pneumonia, Escherichia coli, Staphylococcus haemolyticus, Klebsiella pneumoniae DSM, Staphylococcus hominis, Staphylococcus haemolyticus, Enterobacter faecalis, Staphylococcus saprophyticus, Enterobacter faecalis Pseudomonas lutea. The zones of inhibition were compared with standard antibiotics. Among various solvent extracts tested ethanol leaf extracts exhibited high degree of inhibition followed by ethyl acetate and petroleum ether solvent extracts. The chloroform and acetone extracts did not show any antibacterial activities. The ethanol extract exhibited stronger antibacterial activity against the test bacteria. The zones of inhibition were higher in Staphylococcus hominis and Pseudomonas lutea. The chloroform and acetone extracts did not show any antibacterial activities

Keywords: Antibacterial activity, high degree of Inhibition, Aristolochia bracteolate.