Abstract

FAST DISSOLVING TABLETS

Ganesh Ghale*, Krishna Shimge, Vikram Saruk and Shraddha Pattewar

Abstract

Fast dissolving tablets come into view as one of the well-liked and widely established dosage forms, especially for pediatric patients because of partial growth of the muscular and nervous system and a case of geriatric patients pain from Parkinson’s disorder or hand tremors. Few solid dosage forms like capsules and tablets are present days facing the problems like difficulty in swallowing (dysphasia), resulting in many incidences of non-cooperation and making the therapy unsuccessful. Oral dosage form and oral route are the most favored route of administration for various drugs has limitations like first-pass metabolism, psychiatric patients, laid up and uncooperative patients. FDTs are disintegrating or dissolve quickly in the saliva without a need of water. Fast dissolving tablets are designed to dissolve in saliva remarkably faster, within a few seconds (less than 60 seconds), and those are real fast-dissolving tablets. FDTs formulations contain super disintegrate to enhance the disintegration rate of a tablet in the buccal cavity. FDTs have advantages such as easy portability and manufacturing, accurate dosing, good chemical and physical stability and an ideal alternative for geriatric and pediatric patients. FDTs have disintegrate quickly, absorb faster so, in vitro drug release time develop and this property of drugs (dosage form) enhanced bioavailability. FDT formulations have the advantage of both conventional tablet formulation and liquid dosage form.

Keywords: Fast dissolving tablets, FDTs, Superdisintegrants, Mouth dissolving tablets, MDTs.