Abstract

IN-VITRO ANTI- ARTHRITIC ACTIVITY OF METHANOLIC EXTRACTS OF ALLIUM SATIVUM

T. Kalpana*, B. Chaitanya, P. Mounica, M. Rama Lakshmi, M. Sri Lekha and P. S. Sireesha

Abstract

The present study was aimed to evaluate in-vitro anti- arthritic activity of methanolic extract of Allium sativum which belongs to the family Alliaceae. The in-vitro anti- arthritic activity was evaluated by using Bovine serum albumin denaturation method and Egg albumin denaturation method. The standard drug is considered as mefenamic acid. The phytochemical screening revealed the presence of alkaloids, saponins, flavonoids and tannins. The experimental results showed that the methanolic extracts of Allium sativum possess significant antiarthritic activity. The in-vitro anti- arthritic of Allium Sativum has been reported for the first time.

Keywords: In-vitro, bovine serum albumin, denaturation.