Abstract

A CLASSICAL REVIEW ON PRATINIDHI DRAVYA (SUBSTITUTE DRUG)

Lad Meenal* and Gelohit Rohan

Abstract

Pratinidhi Dravyas are substitute drugs utilize for the drugs which are not available. It mainly deals with rational substitution intentionally selected of crude drugs required for medicinal purpose. This concept is referred from one of the Laghutrayi, Bhavapraksh written in 16th century A.D. As the list of substitute is first of its kind and this Nighantu is considered as latest among classical work in Dravyaguna Shastra. The concept of Pratinidhi dravya(substitute drug) is a need of pharmaceutical industry. Pratinidhi dravya is substitute drug in absence of an original drug. Many (pratinidhi Dravyas) are mention in texts, which are involved many aspect. In Bhavprakash list of pratinidhi dravya is given in Mishraka varga prakarana but in Yogratnakar pratinidhi dravya mentioned separately. The principles to selected pratinidhi Dravya based on similarity of Rasa(Taste), Guna(Property), Virya (Potency) Vipaka most important factor is karma (action). Pratinidhi drug serves to overcome the problem of unavailability of drug due to scarcity, rare or difficult to procure. The purpose of this study is to understand the fundamental Ayurvedic principles behind pratinidhi dravya identification, so that one can proactively apply these in the future discovery of new medicinal plants and therapeutic functions. To study the relationship between a selected list of the original drug and pritinidhi dravya based on Ayurvedic principles and traditional practices Awareness on the use of pratinidhi dravya: To enhance the awareness on possibility of use of pratinidhi dravya concept among Ayurvedic and traditional practitioners. This in way to help to produce good quality herbal product and lend a support in conservation and sustainability of medicinal plants. The Pharmacopeial or extra Pharmacopeial drug should be assessed on the basic fundamentals of as well as resemblance, regional Dravyguna Ayurvedic material medica Rasa, Virya, Vipaka substitution on the basis of synonym, pharmacological and clinical trials. This will enrich the current practices of Pratinidhi Dravyas (SubstituteDrugs) in Ayurvedic science.

Keywords: Pratinidhi dravya, substitute.