Abstract

IN VITRO ANTIOXIDANT PROPERTY OF SIDDHA FORMULATION ‘NAAGA SANGU PARPAM’

Kingsley J.*, Sivakkumar S., Mariappan A., Visweswaran S. and Banumathi V.

Abstract

Free radicals are the natural byproducts of chemical processes, such as metabolism. The human body naturally produces antioxidants to counteract the damaging effects of free radicals. When free radicals accumulate, they may cause a state known as oxidative stress. Chronic oxidative stress can increase the risk of chronic diseases such as heart disease, type 2 diabetes and cancer. To solve this, the method of “Kaya Karpam-Antioxidant” is followed in Siddha medicine. Naaga Sangu Parpam (NSP) is a herbo metal formulation mentioned in Siddha literature which is therapeutically used for treating Moolam (Hemorrhoids), Powthiram (Fistula), Vellai (Leucorrhoea), Vettai (Venereal disease). Siddha medicines not only cure diseases, but it also has rejuvenating property to improve general health and immunity. In this study, the unexplored area of Naaga Sangu Parpam was screened for antioxidant activity using DPPH (2,2-diphenyl-1-picrylhydrazyl), Nitric Oxide Radical Scavenging, ABTS Radical Scavenging activity and Hydrogen Peroxide Scavenging activity. NSP exhibited antioxidant activity against DPPH, Nitric Oxide radicals, ABTS and Hydrogen peroxide with IC50 value of 152.4±4.49, 103.5±7.86, 146.5±18.65 and 156.5±21.64 μg/ml respectively. The result of this study shows promising anti-oxidant activity of Naaga Sangu Parpam (NSP) by in-vitro methods.

Keywords: Antioxidant, Naaga Sangu Parpam, Siddha medicine, Traditional medicine.