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WJPR

World Journal of Pharmaceutical Research

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An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

EVALUATION OF KARAPPAN ENNAI POLYHERBAL FORMULATION FOR ITS ANTI-INFLAMMATORY AND ANTIHISTAMINE ACTIVITIY EFFECTS IN THE TREATMENT OF KARAPPAN (ATOPIC DERMATITIS)

Rajeshwari E.*, Gandhimathi S., Meenakumari R. and Muralidharan P.

Abstract

Karappan ennai is a traditional siddha poly herbal formulation being prescribed for Karappan[1] (Atopic dermatitis in children). The experimental animal method used were Xylene induced ear edema model, Dexamethasone (0.5mg/kg) was used as standard for antiinflammatory effect and Evans blue dye injection method, Citrizine (20mg/kg) was used as standard for anti-histamine effect for its evaluation of the Karappan ennai.[2] Karappan ennai showed significant Anti-inflammatory and Anti-histamine effects in the above study.

Keywords: Karappan ennai, Siddha polyherbal formulation, Karappan (Atopic dermatitis), Anti-inflammatory, Anti-hiatamine activitiy.

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