Abstract

OCULAR SURFACE AND GLAUCOMA MEDICAL THERAPY

Italo Giuffre MD Phd*

Abstract

Purpose: To compare the impact on the ocular surface of glaucomatous patients under monotherapy by latanoprost, tafluprost, bimatoprost and bimatoprost/timolol 0.50% fixed combination. Patients and Methods: This is a single center, clinical and epidemiological study. Fourty glaucomatous patients (20 males; 20 females), age and sex-matched were divided in four groups according to monotherapy (latanoprost 0.005%, tafluprost 0.0015%, bimatoprost 0.03% and bimatoprost 0.03%/timolol 0.50% fixed combination). All of these patients had at least three months follow-up and were under tonometric control. All of these patients were categorized according to a new algorithm to classify the clinical and familiar risk factors. All of them received OSDI and NEI-VFQ-25 questionnaires to evaluate their quality of life under monotherapy. The statistical analysis was performed by Student’s t-test as for demographical data and one-way ANOVA as for the questionnaires results. P

Keywords: Bimatoprost, Bimatoprost/timolol fixed Combination, Latanoprost, NEIVFQ- 25, OSDI, Tafluprost.