Abstract

CARROT JUICE PROTECTS CADMIUM INDUCED GENETIC DAMAGE IN GERM CELLS OF MICE

*K. Rudrama Devi, A. Rajitha and Anuradha S.

Abstract

In the present study, modulating effect of carrot juice against cadmium chloride induced clastogenicity in germ cells of mice. Has been investigated. When animals administered with various doses of carrot juice 20, 40, 80 ml/kg for 30 day and meiotic preparations were made and the prepared were screened for the presence of various types of sperm head abnormalities in germ cells of mice., The obtained results showed non mutagenic nature of plant extract. There was a significant increase in the percentage of aberrant sperms in germ cells of mice at all dose levels However when animals were co-administered seven days prior to the priming experiment with carrot juice, the frequency of aberrant sperms decreased significantly. Thus the results clearly indicate protective nature of carrot juice in cadmium chloride induced cytogenetic damage in germ cells of mice.

Keywords: Cadmium chloride, chromosomal aberrations, carrot juice.