Abstract

STEM CELLS: A BOON TO CANCER THERAPY

Arpit Patidar*, J. S. Vaghela, Arijit Chaudhuri and Vivek Kumar Raman

Abstract

Metastatic cancer cells usually can't be eradicated using traditional surgical or chemo radio therapeutic ways & disease recurrence is extremely common following treatment. On other hand stem cell based therapeutic methods have emerged as terribly engaging treatment choices over the past decades. In present days, stem cells are used as courier vehicles particularly in cancer therapy to deliver variety of targeted proteins & viruses. Multiple types of stem cells have reported to show inherent reaction towards tumors. They have additionally been used as virus & nanoparticle carriers to enhance primary therapeutic efficacies & relative treatment side effects. As well, these cells can be used in immunotherapy, regenerative medicine, cancer stem cell targeted therapy, & anticancerous drug screening applications. However, while using the stem cells for treatment of human cancers seems technically possible, challenges like treatment enduringness & tumorigenesis necessitate further study to enhance therapeutic performance & applicability. This review gives a detail on recent progress towards stem cell based cancer treatments & summarizes treatment advantages, opportunities, challenges & facilitated translation from experimental to clinical studies.

Keywords: stem cell, targeted cancer therapy, cell carrier, delivery agent.