Abstract

A REVIEW ON: ORAL DISPERSIBLE TABLETS

Pawankumar Rai*, Kinjal Modi and Alok Raghav

Abstract

The most preferred route for administration of various therapeutic agents is oral. Recent advances in technology prompted to develop oral disintegrating tablets with improved patient convenience/compliance. Oral disintegrating tablets are the solid unit dosage form which dissolve or disintegrate rapidly in the mouth without use of water or without chewing. The development of oral dispersible tablets has been formulated for pediatric, geriatric, and bed rest patients and for those people as well as patients who may not have access to water. Several formulation provide an opportunity for product line extension especially for elderly persons will have difficulties in taking conventional oral dosage forms because of hand termors and dysphasia. The technologies used for manufacturing of oral disintegrating tablets are either conventional/patented technologies. This review describes various aspects of oral disintegrating tablet formulation, superdisintegrants and technologies developed for it, along with various drugs explored, evaluation tests and marketed formulations in this particular field.

Keywords: ODT, Mechanism of action, Method of preparation, Selection of excipients, Evaluation parameters.