Abstract

SYNTHESIS AND CHARACTERISATION OF 1,3,5 TRIPHENYL-2 PYRAZOLINE FOR ANTIMICROBIAL ACTIVITY

*Mr. Debraj De and Assistant Prof. Mr. Sourav Saha

Abstract

Chalcones, considered to be the precursor of flavonoids and isoflavonoids, are abundant in edible plants. They consist of openchain flavonoids in which the two aromatic rings are joined by a threecarbon α, β-unsaturated carbonyl system. Studies revealed that compounds with a chalcone-based structure have anti-inflammatory, anti-bacterial, anti-fungal, and anti-tumor activities. These activities are largely attributed due to the α, β- unsaturated ketone moiety. Introduction of various substituents into the two aryl rings is also a subject of interest because it leads to useful structure-activity relationship.[1][3][8]

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