Abstract

STUDY ON MANODAIHIK SIDDHANTA WITH SPECIAL REFERENCE TO PREVALENCE AND CORRELATION OF ANXIETY AND DEPRESSION IN PATIENTS WITH CHRONIC RHEUMATOID ARTHRITIS AND ITS MANAGEMENT

*Dr. Sonali Biswas, Dr. Partha. Biswas and Dr. Tapas Bhaduri

Abstract

Background: Anxiety and depression are often appears in longstanding chronic illness. It has been reported that the patients with chronic Rheumatoid arthritis suffers from mental conditions like anxiety and depression. The proper use of psychopharmacological agents in the management of Rheumatoid arthritis with anxiety depression patient still unclear. Objectives: i. To assess the prevalence of anxiety and depression in a population of patient with chronic Rheumatoid arthritis. ii. To assess the level of anxiety and depression in patient with chronic Rheumatoid arthritis and its management by plant medicines. Methods: A randomized double blind placebo control 8 weeks clinical study was conducted in the department of Basicprinciple. The anxiety and depression level in patient with chronic Rheumatoid arthritis were diagnosed clinically by application of different psychological rating scales. Results: 75 patients were randomly assigned into 4 groups. Gr.- A (n=12) served as a control group treated with rice grain powder (3 gm), Gr. B (n= 18) treated with powder of T.Cordifolia, Gr. –C (n=20) treated with root of W. Somnifera (3gm) and Gr. D.(n= 25), treated in combination with T. Cordifolia and W. Somnifera 1.5 gm each. A significant score reduction were found in Hamilton Anxiety Scale, Hamilton Depression Scale and Distress Symptom Scale in each test group following administration of the test drugs. Conclusion: It may be concluded from the our study that T. Cordifolia and W. Somnifera not only possess anti-inflammatory and adaptogenic activity they also reduced blood glucose significantly.

Keywords: Rheumatoid arthritis, Anxiety, Depression.