Abstract

ANTIMICROBIAL AND ANTHELMINTIC ACTIVITY OF PIPER BETLE LEAVES

Manisha Y. Sonalkar* and Sachin A. Nitave

Abstract

The aim of present study is to a comparative evaluation of microbial properties of piper betel leaves against pathogenic microorganism such as bacteria and fungi in agar well diffusion method against some of the standard antibiotics available in the market. Ethanol extract of piper betel leaves were evaluated for Antimicrobial activity against pseudomonas aeruginosa, Staphylococus aureus and Candida albicams and Aspergillus florus strains. Almox and Flucanasole were used as standards for antibacterial and antifungal assay respectively. Ethanol extract showed different degree of activity against antibacterial and antifungal investigation. Ethanolic extract of Piper betel leaves were considerably more inhibitory action against fungi than bacterial strains. The study was also designed to evaluate to anthelmintic properties of ethanolic and aqueous extract of Piper betle Linn. All test sample taken at same concentration ie. (20, 40, 60, 80, 100mg/ml) were tested on indian earth worms (pheritimaposthuma), paralysis time & death of time were consider as assessment of anthelmintic activity. It was noticed in this investigation that the time of paralysis & death of worms was the dose dependent.

Keywords: Piper betle Linn., Antimicrobial activity, Anthelmintic, Ethanolic Extract.