World Journal of Pharmaceutical Research (WJPR) has indexed with various reputed international bodies like :

WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.453

ICV : 90.8

WJPR Citation

	All	Since 2020
Citation	8502	4519
h-index	30	23
i10-index	227	96

User Name :

Password :

Forgot Your Password? | Register

Best Article Awards

World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.

Best Paper Award :
Dr. Dhrubo Jyoti Sen
Download Article: Click Here

Search

Track Your Article

Track Your Article

Abstract

DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR QUANTITATIVE ANALYSIS OF ZOLEDRONIC ACID IN PURE AND PHARMACEUTICAL FORMULATIONS

P. Jitendra Kumar*, Ch. Sharmi Prakash, Ch. Venkatesh, G. Gopi Reddy, G. Satish, D. Rama Brahma Reddy

Abstract

Simple reverse phase high performance liquid chromatography (RPHPLC) method has been developed for the estimation zoledronic acid in pure and pharmaceutical formulation. The separation was done on a 5μ c18column (250×4.6mm) using a mobile phase that consist of the phosphate buffer(pH adjusted ortho phosphoric acid 3.5) and methanol in the ratio of 96:4 (v/v). The flow rate was maintained at 0.7 ml/min The detection was done at 210nm using a uv detector. The retention times of zoledronic acid is 7.8 respectively. The method was validation done according ICH parameters.

Keywords: Zoledronic acid, orthophosphoric acid, rp-hplc, column.

[Full Text Article] [Download Certificate]