Abstract

DEVELOPMENT OF UV SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF ATENOLOL AND AMLODIPINE IN COMBINED TABLET DOSAGE FORM

P. A. Bdul Khadar*, M. Kalyan Naik, D. Lakshmi Bhavani, P. Rajiya, L. S. Babji and V. Srujana

Abstract

Amlodipine and Atenolol drugs are one of the most commonly used hypertensive drugs in India. The history we observed in a 30 years old woman patients used amount of amlodipine 5mg and atenolol 50mg combination of a 100 multiple doses. The test pulse rate was 58 / min and blood pressure 76/40 mmHg. Advance serum creatine at 1.2 mg / dl during the 5 days increased to 4.8 mg / dl. The patient initiated the immunological perspective on the inproper. As the patient uses the beta blocker and the calcium channel blocker, plasmapheresis, calcium gluconate infusion, glucagon, intravenous lipid emulsion, high dosage of insulin dextrose infusion and continuous low-efficiency dialysis have been used. Continue serum creatine levels, hypertension and urinary medicine were supervised, which was improved in the next 1 week and the patient was discharged. Hence we report this interesting content over the combination of Amlodipine and Atenolol drug.

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