Abstract

STABILITY STUDY OF SHIRISHA ASHWAGANDHADI AVALEHA USED IN TREATMENT OF VATAJA PRATISHYAYA (ALLERGIC RHINITIS) ALONG WITH ANU TAILA NASYA - WITH RESPECT TO BASELINE MICROBIAL DIAGNOSTIC MODALITIES

Rozina Khoja*, Cholera M. S. and D. B. Vaghela

Abstract

Background: Allergic Rhinitis (AR) is one such condition created by the harmful effect of altered immunity. Allergic Rhinitis is an Inflammation to the mucosal lining of the nose caused by inappropriate hypersensitivity reaction to an aeroallergen. It is becoming more common with increasing urbanization and industrialization. Aims: To carried out stability study of Shirisha Ashwagandhadi Avaleha with respect to its stability against microbial contamination. Materials and Methods: Sample of prepared drug Shirisha Ashwagandhadi Avaleha was prepared and studied to check microbial contamination at regular time intervals. Results: Every time sample was subjected to the microbiological study from the date of the preparation to the date of last microbiological study. No any contaminations were found in microbiological study. Discussion: Hence the present Study was carried out to observe the stability study of prepared drug Shirisha Ashwagandhadi Avaleha with respect to Microbial Contamination of sample prepared and store in different climatic conditions and temperature. Thus a baseline Microbial profile was studied at regular interval of 1 month for total 6 months (i.e. time for consumption of prepared drug). At the end of study it was found that sample was not showed presence of any Microbes. Conclusion: In microbiological study of the prepared drug Shirisha Ashwagandhadi Avaleha there were no growth found of microorganisms (bacterial or fungal), till 26th August 2018 i.e 06 month from the date of preparation, shows its stability and good shelf life. Hence in present study the stability test of prepared drug Shirisha Ashwagandhadi Avaleha with respect to microbiological findings was negative at room temperature, warm and cold, dry and humid conditions.

Keywords: Allergic Rhinitis, Vataja Pratishyaya, Avaleha, Shirisha Ahwagandhadi Avaleha.